Rev. Johannes Nacken (fl. c. 1867 - 1878) was a German Protestant missionary and member of the Rhenish Missionary Society who operated a medical dispensary near Guangzhou in the 1860s and 1870s. He was apparently adept with both English and Chinese, publishing articles in English-language journals in Guangzhou and Hong Kong as well as becoming an expert on the 13th century lexicographical work Liushugu 六書故 by the scholar Dai Tong (戴侗).