Priscilla Murphy (fl. c. 1950 – 2000) was the first realtor to operate on Sanibel Island in Southwest Florida. Born and raised near Detroit, Michigan, Murphy relocated to Sanibel in the early 1950s after visiting it several times. After opening a ceramics shop, she entered the real estate business, becoming the first realtor based on the island. At that time, the only way to reach the island was by ferry, and its population was consequently fairly small. But in 1963, the Sanibel Causeway opened across San Carlos Bay, making the island much more accessible and attractive to tourists and potential residents. With a friendly and outgoing disposition, Murphy gained a reputation as 'the Queen of Sanibel' and was well-known by the island's residents, many of whom had purchased homes through her. Murphy's mark on the island was so strong that her office on Periwinkle Way has been listed on the Local Register of Historic Landmarks. From the mid-1960s, Murphy published maps and publications dealing with local history and lore, which now serve as valuable resources for researchers on the Postwar development of Sanibel and Captiva.